Supplements for Dry Eyes: What You Need to Know (11 min.)

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To keep eyes comfortable and vision clear, the surface of the eye needs to stay coated with a balanced layer of tears made up of both water and oils. When eyes don’t make enough tears or when tears evaporate too quickly, dry eye syndrome, also known as dry eye disease, can occur.

Table of Contents

• Common Symptoms of Dry Eyes
• Ocular Allergies and Dry Eyes
• How Allergies and Dry Eyes Are Linked
• Supplements for Dry Eyes
• Omega-3 Fatty Acids
• EPA’s Role in Dry Eye Management
• Krill Oil Benefits
• Turmeric and Dry Eyes
• Lutein and Zeaxanthin
• Vitamin D
• Frequently Asked Questions
• Lifestyle Tips for Relief
• Conclusion

If you’re looking for broader guidance beyond dry eye relief, check out in-depth article on the best supplements for eye health to learn which nutrients help protect and support overall vision†.

Common Symptoms of Dry Eyes

Common symptoms of dry eyes may include the following:

• Stinging, burning, or scratchy sensation
• Sensitivity to light
• Redness in the sclera, the whites of the eyes
• A feeling of having something in the eyes
• Difficulty wearing contact lenses
• Blurred vision or eye fatigue

Watery eyes (paradoxically caused by irritation), prompting an overproduction of the watery component of tears.

Ocular Allergies and Dry Eyes: A Common Connection

Ocular allergies, or allergic conjunctivitis, occur when the eyes react to allergens like pollen, dust mites, pet dander, mold, or smoke†. The immune system overreacts to these harmless substances, triggering inflammation and discomfort.

Symptoms of Ocular Allergies

Common symptoms of ocular allergies are similar to dry eyes and may include the following:

• Burning or gritty sensation
• Itchy, watery eyes
• Mucus discharge
• Redness and swelling
• Sensitivity to light

How Allergies and Dry Eyes Are Linked

Many people experience both dry eyes and ocular allergies. Allergies can disrupt the normal tear film by triggering inflammation, which in turn reduces tear quality and increases evaporation. Similarly, having dry eyes can make the eyes more sensitive to allergens.

Certain antihistamines used to treat allergies, especially oral medications, can further dry out the eyes, compounding symptoms.

Are there Supplements for Dry Eyes?

Several nutritional supplements for dry eyes have been studied for their potential to alleviate symptoms and support tear production†.

Omega-3 Fatty Acids

Omega-3s are essential fats known for their anti-inflammatory properties and are the most researched supplements for dry eyes†. They are found in fish oil and certain plant oils. Some studies have suggested that omega-3 supplements may improve tear production and reduce dry eye symptoms†. However, the Dry Eye Assessment and Management (DREAM) study, a 12-month study of 349 adults published in the New England Journal of Medicine, found no significant benefit of omega-3 supplements (3000 mg daily) over placebo for dry eye disease.

When considering omega-3 fatty acids for managing dry eye disease (DED), both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been studied. However, recent studies suggest that EPA may play a more significant role in alleviating dry eye symptoms†.

EPA’s Role in Dry Eye Management

A meta-analysis published in 2023 looked at 19 randomized controlled trials (RCTs) with 4,246 adults diagnosed with dry eye disease. The studies included were published between 2005 and 2022. Key findings included:

• Inflammation Reduction: Markers indicating eye inflammation were reduced in those taking omega-3†.
• Tear Production: Participants taking omega-3 showed increased tear production†.
• Symptom Improvement: Omega-3 supplements significantly improved dry eye symptoms compared to placebos†.
• Tear Stability: Omega-3 intake improved the stability of the tear film (how long tears stay on the eye surface)†.

The meta-analysis concluded that omega-3 fatty acid supplementation is effective in managing dry eye disease†. It helps alleviate symptoms, enhances tear production and stability, and reduces inflammation†. These findings support the use of omega-3 supplements as a beneficial treatment option for individuals suffering from dry eye disease†.

Recommended Omega-3 Intake

For individuals considering omega-3 supplements to manage dry eye symptoms, formulations with a higher EPA to DHA ratio may offer more significant benefits†. Talk with your ophthalmologist or eye care provider before starting any new supplement regimen to ensure you’re doing what’s best for your individual health needs†.​

Krill Oil Dry Eye Benefits

Krill oil is also being explored as one of the promising supplements for dry eyes, although research is still emerging†. Krill oil contains omega-3s and the antioxidant astaxanthin. Some believe it may be more bioavailable than fish oil†. However, research specifically on krill oil for dry eyes is limited. A small 30-day study of 60 adults aged 51-72 years with mild-to-moderate dry eye disease had participants take 6 mg of astaxanthin twice daily (for a total of 12 mg astaxanthin). While the study had positive results†, it was a single-group study without a control group, and a month isn’t enough time to assess long-term effects.

Does Turmeric (Curcumin) Have a Role in Treating Dry Eyes?

Curcumin, the active compound in turmeric, has anti-inflammatory properties†, so it makes sense that this dietary supplement might have a positive role in treating dry eyes†. However, the only studies evaluating the impact of turmeric and dry eyes have been tiny and inconsequential.

A multi-ingredient 8-week study (with results published in 2024) recruited 155 participants, all suffering from dry eye disease. Half the participants were assigned to take 20 mg of lutein, 4 mg of zeaxanthin isomers, 200 mg of curcumin curcuminoids, and 600 IU of vitamin D3 per day, while the other half received a placebo. Tear volume and ocular symptoms were assessed on days 14 and 56. Researchers found that the group who received the supplements, rather than the placebo, showed improvements in tear production†, stability†, and quality†, while also reducing ocular surface damage†, inflammation†, and dry eye symptoms†. These results suggest that multi-ingredient formulations, including turmeric, may be effective supplements for dry eyes when used in conjunction with standard treatments.

Lutein and Zeaxanthin for Eye Health

Lutein and zeaxanthin are natural pigments called carotenoids that give certain fruits and vegetables bright yellow, orange, and green colors. They are found in high amounts in leafy greens like spinach and kale, as well as in corn, peppers, and eggs. These nutrients are known for their role in filtering harmful light and supporting clear vision†.

These carotenoids are known for supporting eye health†. The same study mentioned above found that a supplement containing lutein and zeaxanthin improved dry eye symptoms†. Research indicates that high-dose supplementation with lutein and zeaxanthin, at levels exceeding 10 mg daily, can enhance ocular health by increasing macular pigment optical density†.​

(Bonus: Learn how lutein benefits healthy skin in addition to eye health†.)

Vitamin D and Dry Eyes

Studies suggest that vitamin D deficiency may be linked to dry eye disease†. In the study titled “Effect of Oral Vitamin D Supplementation on Dry Eye Disease Patients with Vitamin D Deficiency,” published in Clinical and Experimental Optometry in April 2023, 100 patients diagnosed with dry eye disease and confirmed vitamin D deficiency (blood levels below 20 ng/mL) were recruited to determine if taking vitamin D supplements can help alleviate symptoms of dry eyes in individuals with low vitamin D levels. In the randomized controlled trial, the participants received standard dry eye treatment (artificial tears), but only half were given additional vitamin D supplements for 8 weeks. Researchers assessed the following parameters before and after the 8 weeks:

• Schirmer’s Test: Measures tear production.
• Tear Break-Up Time (TBUT): Evaluates tear film stability.
• Tear Osmolarity: Assesses the salt concentration in tears, indicating tear quality.

After 8 weeks, the vitamin D group showed significant improvements in all three tests, indicating better tear production†, stability†, and quality†, while the control group experienced minimal to no improvement. The study concluded that supplementing vitamin D in patients with both dry eye disease and vitamin D deficiency can significantly enhance the effectiveness of standard dry eye treatments†.

Frequently Asked Questions

Can medications impact dry eyes?

Yes, certain medications, including antihistamines, decongestants, antidepressants, diuretics, beta-blockers, and isotretinoin (a medication used for acne treatment), can contribute to dry eye symptoms.

Does diet help with dry eyes?

A diet rich in omega-3 fatty acids, antioxidants, and hydration can support eye health†. Consuming fatty fish, leafy greens, nuts, and seeds may help reduce symptoms†.

Is cream or powder eyeshadow better for dry eyes?

Cream-based eyeshadows are generally recommended for individuals with dry or sensitive eyes. Their emollient texture adheres better to the eyelid, minimizing the risk of particles flaking off into the eye, which can exacerbate dryness. Cream-based formulations provide a smoother application and are less likely to cause irritation†.

Powder eyeshadows, especially those containing glitter or shimmer, can release fine particles that may enter the eye, potentially leading to discomfort or dryness. Additionally, powder formulations can accentuate dryness on the eyelids, making them less suitable for those with dry eye conditions.

When applying eye makeup, avoid applying eyeliner or eyeshadow directly to the inner rim of the eyelids (the waterline), as this can increase the likelihood of particles entering the eye and disrupting the tear film. Regularly clean brushes and applicators to prevent introducing irritants or bacteria into the eye area. Look for eye makeup products labeled as hypoallergenic and free from common irritants to reduce the risk of exacerbating dry eye symptoms.

Does menopause impact dry eyes?

Yes, hormonal changes during menopause can decrease tear production, increasing the risk of dry eyes.

Are men or women more likely to suffer from dry eyes?

Women are more likely to experience dry eyes, partly due to hormonal changes from pregnancy, menopause, and contraceptive use.

Is there any reason someone with dry eyes or ocular allergies might benefit from taking a daily multivitamin?

Yes, someone with dry eye might benefit from taking a multivitamin, especially if their diet is low in key nutrients that support eye health. While a multivitamin isn’t a treatment for dry eye disease, it can complement other supplements for dry eyes by helping address underlying nutrient deficiencies.† A multivitamin can help:

• Cover Nutritional Gaps: Many people don’t get enough essential vitamins, such as A, C, D, and E, through diet alone. These vitamins help support the eye’s surface, reduce inflammation, and promote healthy tear production†.
• Support Tear Production: Vitamin A is essential for maintaining the health of the cornea (the outer surface of the eye) and for proper tear function†. A deficiency can lead to dryness and irritation.
• Reduce Inflammation: Antioxidants (like vitamins C and E) help reduce oxidative stress and inflammation that may contribute to dry eye symptoms†.
• Correct Underlying Deficiencies: Studies have found that deficiencies in vitamin D and B vitamins (like B12) are sometimes linked to more severe dry eye symptoms†. A multivitamin can help address these gaps†. (Cooper Complete multivitamins contain 2000 IU (50 mcg) of vitamin D3 as a recommended baseline level of supplementation for all adults.)
• Convenience: For individuals who struggle to manage multiple supplements, a high-quality multivitamin can provide a balanced base of nutrients in a single daily dose†.

Are There Lifestyle Tips to Reduce Dry Eye Discomfort?

• Avoid Direct Airflow to the Face—Limit exposure to fans, air conditioners, car vents, or heaters blowing directly at your face, as they can speed up tear evaporation†.
• Avoid Smoke Exposure—Do not smoke or be around those who do, and avoid wood fires and campfires.
• Blink More Frequently and Fully—Intentional blinking helps spread tears evenly across your eyes. This is especially important during prolonged screen time or reading.
• Consider an Air Purifier—To reduce indoor allergens
• Eat Well—Incorporate omega-3 fatty acids, leafy greens, and foods rich in antioxidants (essentially the color of a rainbow) to support eye health†.
• Follow the 20-20-20 Rule—When using screens, look at something 20 feet away for 20 seconds every 20 minutes. This reduces eye strain and reminds you to blink more often.
• Keep Windows Closed—During high pollen days
• Limit Contact Lens Use—If contact lenses worsen your dry eye symptoms, try reducing wear time or ask your eye doctor about daily disposable or more moisture-friendly lenses.
• Remove Eye Makeup Thoroughly—Leftover makeup can block the tear glands. Use a gentle, oil-free remover and clean along the lash line each night.
• Shower and Change Clothes—After spending time outdoors during allergy season.
• Stay Well-Hydrated—Drink plenty of fluids throughout the day to stay hydrated. Aim for at least 8 cups of water daily unless otherwise directed by your physician or healthcare provider.
• Use Artificial Tears or Lubricating Eye Drops—Over-the-counter drops can offer temporary relief. Artificial tears help lubricate and flush out allergens, while antihistamine drops target allergy-related itching and redness. Mast cell stabilizers prevent the release of histamine before symptoms begin. Choose preservative-free options for frequent use, as preservatives (like BAK) can cause irritation with frequent use. Look for thicker gels or ointments for nighttime use, and pick a formula based on your main symptoms.
• Use a Humidifier—Adding moisture to indoor air, especially in dry climates or during winter, can help prevent tear evaporation.
• Wear Wraparound or Moisture Chamber Glasses—Protect your eyes from wind, sun, and dry air by wearing wraparound or moisture chamber glasses.

Conclusion: Supplements Are Just One Piece of the Puzzle

While certain supplements—like omega-3 fatty acids, vitamin D, lutein, and possibly turmeric—show promise in supporting eye health and easing dry eye symptoms†, they aren’t magic fixes. Research is still evolving, and some studies have shown mixed results. Supplements may help reduce inflammation†, improve tear quality†, and support the eye’s surface†, especially for people with specific nutrient deficiencies. However, they work best when used in conjunction with other dry eye treatments and lifestyle modifications†.

Dry eye disease and ocular allergies are complex conditions with many causes and contributing factors. Managing them often takes a combination of strategies, including using artificial tears, protecting your eyes from environmental triggers, staying hydrated, adjusting screen habits, and eating a balanced, nutrient-rich diet. Supplements can be a helpful part of that plan, but they’re just one tool in the toolbox†.

Always talk to your eye doctor before starting any new supplement, especially if you’re already taking medication or have ongoing health conditions, to develop a plan that best suits your individual needs.

Want to dive deeper into vision support? Read our full guide on the best supplements for eye health to learn about vitamins, minerals, and antioxidants that support lifelong visual wellness†.

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About the Author: Jill Turner is the President of Cooper Complete® Nutritional Supplements, where she oversees product development and customer experience. She enjoys writing about vitamins, supplements, and preventive health to help consumers make informed, science-backed decisions.

Cooper Complete July 22, 2025