Supplements for Gum Disease: Supporting Oral Health Naturally

Gum disease, also known as periodontal disease, is a common condition that affects the health of your gums and the structures supporting your teeth. While good oral hygiene practices like brushing, flossing, and regular dental checkups are essential, certain dietary supplements may support oral health and help manage gum disease. Let’s explore some evidence-based supplements for gum disease and how they may contribute to a healthier smile.
What is Gum Disease?
Gum disease is an inflammatory condition caused by the accumulation of plaque and bacteria around the teeth and gums. Early-stage gum disease, or gingivitis, is marked by redness, swelling, and bleeding gums. If left untreated, it can progress to periodontitis, a more severe form that can lead to tooth loss and systemic health issues such as cardiovascular disease and diabetes. Nearly half of all adults have some form of gum disease, impacting more than 42 percent of adults over age 30. By age 65, almost 60 percent of adults have some form of periodontal disease. The disease is more common in men than women and affects more than half of men and 35 percent of women.
Can Supplements Help with Gum Disease?
While supplements cannot replace professional dental care or twice daily brushing and regular flossing, certain nutrients play a vital role in maintaining gum health. They may help reduce inflammation, promote tissue repair, and strengthen the immune system, creating a supportive environment for oral health.

Natural Vitamin C Supplement
Natural Vitamin C Supplement contains 850 mg of vitamin C (as calcium and magnesium ascorbates), plus citrus bioflavonoids to support cells, immune health, and healing.†
$29.98 Add to cartTop 6 Supplements for Gum Disease
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Vitamin C
Vitamin C is essential for collagen production, a key component of gum tissue. It also acts as a powerful antioxidant, reducing inflammation and supporting the healing of damaged gums. Research has shown that individuals with lower vitamin C levels are more prone to gum bleeding and periodontal disease. A systematic review of 14 articles that included seven cross-sectional studies suggests that lower vitamin C intake and blood levels were negatively related to gum disease. The individuals with lower dietary intake or blood levels of vitamin C showed more progression of gum disease than the controls.
Citrus fruits, bell peppers, and strawberries are food sources of vitamin C. From a dental health perspective, the literature also reports that citrus fruits and juices can cause erosive tooth wear due to their high acidity.
Cooper Complete Basic One multivitamins contain 150 mg of vitamin C per serving, while Original multivitamin includes 500 mg per serving (250 mg per 4 tablets in the morning and again in the evening). A standalone vitamin C supplement with citrus bioflavonoids that contains 850 mg of vitamin C is available.
(Learn additional benefits of vitamin C.)
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Vitamin D
Vitamin D supports bone health and immune function, both of which are crucial for maintaining healthy gums and teeth. Although the research has been mixed, some studies suggest that adequate vitamin D levels can reduce the risk of gum inflammation and attachment loss. A 2023 study of 451 people in a double-blind, randomized, controlled trial evaluated vitamin D level and gingival health at baseline. For three months, subjects received either a placebo, 500 IU (12 ½ mcg), 1000 IU (25 mcg) or 2000 IU (50 mcg) vitamin D. Each month, gingival scores were recorded to assess the anti-inflammatory effect. Researchers found vitamin D administration negatively correlated with gingival index score. It’s important to note that vitamin D levels were 32 to 37 ng/mL and that an optimal blood vitamin D level is 30-35 ng/mL.
Sardines, mackerel, salmon and other oily fish contain vitamin D, and breakfast cereals and many dairy products are fortified with vitamin D. Cooper Complete multivitamins contain 2000 IU (50 mcg) of vitamin D per serving, and standalone vitamin D supplements are available in 1000 IU (25 mcg) and 5000 IU (125 mcg) options.
(Read how vitamin D provides health benefits throughout the body.)

100 mg CoQ10 Ubiquinol Supplement
KanekaQH®, the reduced form of coenzyme CoQ-10, provides advanced antioxidant support and promotes cellular energy and optimal heart and immune function.†
$37.98 Add to cart-
Coenzyme Q10 (CoQ10)
CoQ10 is a naturally occurring antioxidant that is particularly concentrated in the gums. Low levels of CoQ10 have been associated with periodontal disease. Supplementation may help reduce gum inflammation and improve gum health by boosting cellular energy and antioxidant defenses.
However, great research is lacking, and what’s available is that CoQ10 administered intra-pocket in the mouth was better than topically or orally. A systematic review and meta-analysis of clinical trials conducted in 2022 pulled research from 1980 to August 2020. Of 269 records, 11 trials were included in the meta-analysis using a random-effect model. Of interest were plaque index, bleeding index, gingival index, clinical attachment level and pocket depth. The review showed that CoQ10 use in combination with scaling and root planing could improve periodontitis.
Meat, fish and nuts contain CoQ10, but the amounts are low enough that increasing levels in the body is challenging without supplements. Cooper Complete Original multivitamin includes 100 mg of CoQ10 per daily serving, and standalone CoQ10 supplements of 50 and 100 mg are available.
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Omega-3 Fatty Acids
Omega-3 fatty acids, particularly EPA and DHA, have potent anti-inflammatory properties and might be a good supplement to help manage gum disease. Sadly, there’s not a lot of research, even though periodontal disease is so common. A review and meta-analysis in 2020 found 14 studies reviewing omega-3 fatty acids in periodontal therapy and included six in their analysis. All were small – encompassing 265 participants total, and half of those were assigned to the placebo group. In various studies, amounts of omega-3s varied. One study inexplicably administered 25.44 mg EPA/DHA per day (an incredibly small amount), two studies administered 900 mg per day, and three studies had participants take 3000 mg (1000 three times daily). Three of the studies paired the omega-3 with either a 75 mg or 81 mg low-dose aspirin. Four of the studies lasted six months, while one study was 12 weeks, and another was one year. Most studies did not specify the amount of EPA and DHA in the omega-3 fatty acids. Despite all these inconsistencies, the authors report that omega-3 fatty acids have benefits in reducing pocket depth and attachment gain.
Salmon, sardines, mackerel, and other oily fish contain long-chain omega-3 fatty acids, while flaxseeds and walnuts are sources of short-chain omega-3 fatty acids. Cooper Complete Advanced Omega-3 softgels contain 1400 mg Omega-3 fatty acids in two softgels, while the liquid omega 3 contains 2600 mg Omega-3 fatty acids per teaspoon.
(Learn more about the benefits of omega-3 throughout the body.)
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Zinc
Zinc supports immune function and wound healing and is a key nutrient in oral health. It is found in saliva, dental plaque, and dental enamel hydroxyapatite. Zinc helps reduce plaque buildup and bacterial growth in the mouth, protecting against gum disease.

Advanced Daily Probiotic Supplement
Advanced Daily Probiotic supplement contains a proprietary blend of 4 strains and 35 billion CFU probiotics to support gut microflora and immune health.†
$46.98 Add to cartMeat, shellfish, dairy products, legumes, nuts and seeds, and whole grains all contain zinc, although plant-based foods also have phytates that can bind zinc and inhibit absorption. Cooper Complete multivitamins contain 15 mg of zinc per serving, while Eye Health has 25 mg of zinc per serving. A standalone Zinc Supplement provides 25 mg per serving. Note: Because the daily upper limit of zinc is 40 mg, the standalone zinc supplement should not be taken with Eye Health.
(Learn more about the health benefits of zinc.)
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Probiotics
Probiotics may benefit oral health by balancing the bacterial environment in the mouth, lowering the mouth’s pH, and preventing plaque bacteria from forming. Certain strains, such as Lactobacillus and Bifidobacterium lactis, have been shown to reduce plaque, gingival inflammation, and bad breath.
Yogurt, fermented milk products like kefir, buttermilk and cottage cheese (with “live and active cultures), and fermented foods such as pickles, sauerkraut, miso and tempeh all contain probiotics. Probiotic-fortified chewing gum also exists. Cooper Complete Advanced Daily Probiotic contains four strains of probiotics, including Bifidobacterium lactis and Lactobacillus.
Supporting Gum Health Through Diet and Lifestyle
In addition to supplements, adopting a nutrient-rich diet and healthy lifestyle can significantly impact gum health. Consider these tips:
- Hydrate: Drink plenty of water to keep your mouth moist and wash away food particles and bacteria.
- Eat Well: Focus on foods rich in vitamins and minerals, such as leafy greens, nuts, and lean proteins.
- Limit Sugar: Reduce sugary snacks and beverages to prevent plaque buildup.
- Do Not Smoke: Smoking weakens the immune system and increases the risk of periodontal disease.
When to Consult a Dentist
Supplements for gum disease are not a substitute for professional dental care. If you’re experiencing symptoms of gum disease, such as persistent bad breath, swollen gums, or loose teeth, consult your dentist promptly. Early intervention is key to preventing further complications.
Final Thoughts Regarding Supplements for Gum Disease
Integrating supplements for gum disease into your oral care routine can provide additional support for gum health. Vitamin C, vitamin D, CoQ10, omega-3s, zinc and probiotics all play unique roles in reducing inflammation and promoting tissue repair. Paired with proper dental hygiene and regular checkups, these supplements can help you maintain a healthy smile and overall well-being.
Always consult your physician, dentist, periodontist or health care provider before adding new supplements, especially if you have existing medical conditions or are taking medications.