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Advanced Daily Probiotic supplement contains a synbiotic blend of 16 strains and 40 billion CFU probiotics and prebiotics to support gut microflora and immune health.†

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One-time Purchase


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Gluten-Free Non-GMO

*Daily value not established.

Advanced Daily Protiobic
Supplement Facts

Serving Size: 2 vegetarian acid-resistant capsules
Servings Per Container: 30
Ingredient Amount Per Serving
% Daily
Proprietary Blend
Yielding 40 Billion CFU: Nutraflora® short-chain FOS prebiotic fiber, Lactobacillus acidophilus, Lactobacillus plantarum, Lactococcus lactis, Lactobacillus paracasei, Bifidobacterium lactis HN019, Bifidobacterium breve, Streptococcus thermophilus, Bifidobacterium lactis (infantis), Bifidobacterium bifidum, Lactobacillus salivarius, Lactobacillus casei, Lactobacillus brevis, Bifidobacterium longum, Lactobacillus gasseri, Lactobacillus bulgaricus, Lactobacillus rhamnosus
560 mg *
*Daily Value not established.

Other Ingredients: Capsule (hydroxypropyl methylcellulose, pectin, glycerol, purified water), and sunflower lecithin

Cooper Complete Gluten Free iconCooper Complete Non GMO Icon

This dietary supplement is gluten-free and Non-GMO.

While we strive to ensure the label information on this site represents the label on the product available for purchase, products are updated from time to time. Please consult the label on the product you purchase for the most accurate ingredient and allergen information.

Nutraflora® is a registered trademark of Corn Development Products, Inc.

Item Number: 304
SKU: 816899005022
GTIN-12 (UPC-A): 202634-60-PL-84121312 V0522

What It Is

Probiotics are live beneficial microorganisms that live in our gut. This daily probiotic supplement provides 16 strains and 40 billion CFU of LactobacillusLactococcusBifidobacterium and Streptococcus cultures probiotics plus a short-chain prebiotic fructooligosaccharide (FOS) that works synergistically with probiotics to support gut microflora and immune health. Prebiotics fuel the gut’s beneficial “probiotic” bacteria. The prebiotic fructooligosaccharide (FOS) promotes healthy gut bacteria and mineral absorption in the gut.

How to Use:

As a dietary supplement, take two (2) vegetarian acid-resistant capsules daily or as directed by your health care professional. Each bottle contains 30 servings.

How It Helps

This everyday Advanced Daily Probiotic supplement provides 16 strains and 40 billion CFU probiotics plus Nutraflora® short-chain fructooligosaccharides (FOS) prebiotic fiber to support gut microflora and immune function.

Immune Health

A meta-analysis of 18 randomized clinical trials including 1,047 participants (with 514 in the probiotic group) on Lactobacillus plantarum and immune health suggests L. plantarum enhances immune response by modulating pro-inflammatory and anti-inflammatory cytokines.

Blood Pressure Support

A review of nine clinical trials, including 534 adults  (18 years and older), found a significant reduction in systolic (3.56 mm Hg) and diastolic (2.38 mm Hg) compared to placebo. However, the Heart Outcomes Prevention Evaluation (HOPE Study) found reducing systolic blood pressure by 3.3 mm Hg and diastolic blood pressure by 1.4 mm Hg was associated with a 22 percent reduction in stroke, heart attack, or cardiovascular event resulting in death.

Allergic Rhinitis Relief

A review of 23 studies found some evidence that lactobacillus probiotics may help improve symptoms and quality of life of seasonal hay fever sufferers.

Cholesterol Management

A meta-analysis of 15 studies with 976 subjects found lactobacillus probiotics reduced total cholesterol by about 10 mg/dL and LDL by about 9 mg/dL in patients with or without hypercholesterolemia. However, Lactobacillus probiotics did not change HDL cholesterol.

Lung and Respiratory Tract Support

A 2015 review of 12 studies indicated people taking probiotics may have fewer and shorter upper respiratory infections. Lactobacillus seems to prevent respiratory tract infections in most adults, while bifidobacteria seems to prevent respiratory tract infections in otherwise healthy adults.

Digestive Health Support

Advanced Daily Probiotic supplement is intentionally formulated to contribute to a healthy digestive tract and support optimal gastrointestinal health. (Read the blog about the health benefits of probiotics to learn more.)

As a dietary supplement, adults take two (2) capsules daily or as directed by their health care professional. Each bottle contains 60 vegetarian acid-resistant capsules.

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What Our Customers are Saying

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Reviews of Advanced Daily Probiotic Supplement

  1. I want to let you know that I trust Cooper Complete products very much — I love them all! I feel so great that if I forget some supplement, I realize what is missing. It truly is an overall healthy feeling! Thank you, thank you!

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Customer Q&As

If you have questions, we have answers. See what real people are asking about Cooper Complete products.

13 Questions
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Should a healthy 79-year-old woman take this probiotic and your multivitamin?


A probiotic and multivitamin both support your health.  A multivitamin is meant to help with nutrient deficiencies in your diet. A probiotic supports a healthy gut microbiome and does not replace nutrients. Probiotics have both therapeutic benefits and probiotics have preventive properties as well. For example, they support a healthy immune system. Even things you might not consider a health condition, such as allergies, can benefit from taking a probiotic. If you’re interested in adding a probiotic to your supplement routine, your healthcare provider can help you determine if it is right for you.  You can read more about probiotic benefits here.



Can I use a pill organizer for the Advanced Daily Probiotic?


Because probiotics are living microorganisms, storage is important. They need to be protected from light and moisture. We recommend keeping them in the original bottle in a cool, dry location. We recommend not using a weekly pill organizer as they are usually not airtight and could impact the effectiveness of the probiotic.


Why don’t you store the probiotic in a glass container? I heard those are better than plastic.


Probiotics need to be stored in a container that will block light and humidity. Options for packaging that will ensure product freshness include high-density polyethylene (HDPE), Polyethylene Terephthalate (PET),  or glass bottles. All of these packaging options provide barriers to water vapor and UV rays. HDPE bottles, such as those used for Advanced Daily Probiotic,  are lightweight, durable, and won’t break like glass might.


On the bottle it states 60 capsules for 60 servings. On your description it states take 2 and there is 30 servings per bottle. Which is it?


The correct amount is 30 servings per bottle.


Do probiotics help prevent urinary tract infections?

Also, if taking Cooper calcium and Cooper complete multi, when should probiotics be taken?



Antibiotics used in treating UTI infections reduce the number of lactobacilli in the urinary system and may destroy the existing natural barrier of the urinary system to fight infections. Probiotics can help restore the balance. There is some research suggesting probiotics may be beneficial for preventing recurring UTIs as well as restoring the balance after taking antibiotics; however, further research is needed to confirm this.

You may take probiotics with your other supplements without affecting the effectiveness of the probiotic or other supplement/vitamin.



Does this product contain soy?


Cooper Complete Probiotic does not contain soy, but is manufactured in a facility that manufactures products containing soy. Although the equipment is cleaned between product runs, cross-contamination could occur.


What is your opinion on probiotics for mood and brain health?


As always we look to scientific research as a basis for our opinion.

Your brain and gut communicate; known as the gut-brain axis. Recent studies have shown that consuming probiotics may help improve your mood. Specifically, strains B. longum, and B. bifidum, both found in Cooper Complete Advance Probiotic, have been researched for therapeutic benefits for anxiety and depression.


Should probiotics be taken in the am or pm?


It does not matter if it is morning or evening; the most important thing is consistency, so take the Advanced Daily Probiotic Supplement at a time convenient for you.


Does this product contain soy?


No, Cooper Complete Advanced Daily Probiotic supplement does not contain soy.


Can I take this product if I am also taking anticoagulant medication (i.e., blood thinners)?


If you are taking anticoagulant medication, we recommend consulting your doctor before adding any supplements to your diet.


Why doesn’t this probiotic supplement require refrigeration?


Advanced Daily Probiotic Supplement vegetarian capsules are acid-resistant (and bile-resistant) and break down in the small intestine rather than the stomach. Intestinal fluid dissolves the capsule content directly into the small intestine. The capsules are shelf-stable due to a cryoprotectant stabilization process. This product should be stored in a cool, dry place away from moisture.


What is Fructooligosaccharide (FOS)?


Fructooligosaccharide (FOS), a prebiotic, has been well-studied and found to modulate gut bacteria, and improve the absorption of minerals in the gut.


How many probiotic strains are in the probiotic?


Advanced Daily Probiotic Supplement contains 16 beneficial strains of Lactobacillus, Lactococcus, Bifidobacterium, and Streptococcus cultures, including Bifidobacterium lactis NH019 which has been clinically researched to support immune and gastrointestinal function.