Cognitive Health Magnesium L-Threonate Powder 1 g

Cognitive Health Magnesium L-Threonate Powder has a one-year shelf life from the date of manufacture, which is shorter than our other products due to the natural flavors used. Taste and aroma can weaken over time. To ensure you enjoy this product with the best flavor and scent, we set a shorter shelf life and make smaller, more frequent batches. Because of this, we suggest you not purchase more than a 3- to 4-month supply at any one time.

Magnesium L-Threonate Powder has a hint of berry flavor. It’s a light, subtle flavoring of mixed berries, so it shouldn’t be offputting for those adverse to more potent, pronounced flavors.

No—these forms of magnesium are not typically associated with a laxative effect. Unlike common magnesium salts such as magnesium oxide or magnesium citrate, which can draw water into the intestines and cause loose stools, the forms used in Cognitive Health Magnesium L-Threonate Powder are designed for targeted absorption and brain support, not digestive action†.

Because they’re highly bioavailable and better absorbed at the cellular level†, magnesium L-threonate, magnesium acetyl taurinate, and magnesium glycerophosphate are generally well-tolerated—even for those who are sensitive to magnesium’s gastrointestinal side effects†.

General Safety

This product is formulated with highly bioavailable forms of magnesium to support cognitive health, emotional balance, and sleep quality†. When used as directed, magnesium is well tolerated by most.† It may interact with certain prescription medications, so check with your pharmacist or healthcare provider if you have concerns.

Potential Interactions

• Antibiotics (e.g., tetracyclines, fluoroquinolones): May reduce effectiveness, so take magnesium at least 2 hours before or 4–6 hours after.
• Thyroid medications (e.g., levothyroxine): May interfere with absorption if taken together.
• Bisphosphonates (osteoporosis medications): May be less effective if taken at the same time as magnesium.
• Diuretics or blood pressure medications: Magnesium may influence how these medications work.
• Sedatives or sleep aids: Magnesium’s calming properties may have an additive effect.

Cognitive Health Magnesium L-Threonate Powder is formulated to support brain health, memory, and focus without causing drowsiness†. Many people take it in the morning or afternoon for cognitive support, while others prefer the evening to also support relaxation and sleep quality.† Magnesium L-threonate doesn’t act like a sedative; it helps promote calm focus and mental clarity.† If you’re unsure, try taking it at a time when you can see how your body responds, then adjust to fit your routine.

For sleep support, take Cognitive Health Magnesium L-Threonate Powder in the evening, about 1–2 hours before bedtime.† This timing allows magnesium’s calming properties to support relaxation, GABA activity and healthy melatonin production, helping ease you into restful sleep†. Mix one scoop with water or your favorite beverage as part of your nightly routine.

The powder and capsule versions both support brain health, but they differ in format, flavor, and magnesium composition. See the comparison below for details.†

You may consider combining both forms of magnesium for more comprehensive support, especially if you’re looking to target both mind and body wellness.†

You want full-body and brain support

• Glycinate helps restore overall magnesium levels throughout the body†

• L-Threonate helps increase magnesium concentration in the brain†

You deal with both muscle tension and mental fatigue

• Glycinate supports muscle relaxation and may ease physical stress†

• L-Threonate may promote mental clarity and emotional balance†

You’re looking to improve sleep from multiple angles

• Glycinate helps the body unwind and relax before bed†

• L-Threonate may support sleep quality by promoting healthy brain activity†

Mix one scoop (3.3 grams) of the powder with water or your favorite beverage. The powder is a very mild natural mixed berry flavor.

Magnesium is essential for synaptic plasticity, neurotransmitter activity, and mitochondrial energy in brain cells. Increased brain magnesium may help support working memory, learning, and attention, especially in older adults†.

This powder features three advanced forms of magnesium—L-threonate, acetyl taurinate, and glycerophosphate—which are formulated for optimal brain support†. Magnesium L-threonate (Magtein®) is the only form shown to cross the blood-brain barrier and increase brain magnesium levels, supporting memory, focus, mood, and sleep quality†.